Top Architecture & Design MCP Servers - Ranked by GitHub Stars

14 of 14 servers

genomoncology/biomcp

523

Biomedical research MCP server providing access to PubMed, ClinicalTrials.gov, and MyVariant.info.

github.com/genomoncology/biomcp

the-momentum/apple-health-mcp-server

212

An MCP server that provides access to exported data from Apple Health. Data analytics included.

github.com/the-momentum/apple-health-mcp-server

wso2/fhir-mcp-server

123

Model Context Protocol server for Fast Healthcare Interoperability Resources (FHIR) APIs. Provides seamless integration with FHIR servers, enabling AI assistants to search, retrieve, create, update, and analyze clinical healthcare data with SMART-on-FHIR authentication support.

github.com/wso2/fhir-mcp-server

JamesANZ/medical-mcp

An MCP server that provides access to medical information, drug databases, and healthcare resources. Enables AI assistants to query medical data, drug interactions, and clinical guidelines.

github.com/JamesANZ/medical-mcp

the-momentum/fhir-mcp-server

MCP Server that connects AI agents to FHIR servers. One example use case is querying patient history in natural language.

github.com/the-momentum/fhir-mcp-server

Narasimhaponnada/mermaid-mcp

AI-powered Mermaid diagram generation with 22+ diagram types including flowcharts, sequence diagrams, class diagrams, ER diagrams, architecture diagrams, state machines, and more. Features 50+ pre-built templates, advanced layout engines, SVG/PNG/PDF exports, and seamless integration with GitHub Copilot, Claude, and any MCP-compatible client. Install via NPM: `npm install -g @narasimhaponnada/mermaid-mcp-server`

github.com/Narasimhaponnada/mermaid-mcp

OHNLP/omop_mcp

Map clinical terminology to OMOP concepts using LLMs for healthcare data standardization and interoperability.

github.com/OHNLP/omop_mcp

longevity-genie/biothings-mcp

MCP server to interact with the BioThings API, including genes, genetic variants, drugs, and taxonomic information.

github.com/longevity-genie/biothings-mcp

longevity-genie/gget-mcp

MCP server providing a powerful bioinformatics toolkit for genomics queries and analysis, wrapping the popular `gget` library.

github.com/longevity-genie/gget-mcp

longevity-genie/opengenes-mcp

🎖️ 🐍 🏠 ☁️ - MCP server for a queryable database for aging and longevity research from the OpenGenes project.

github.com/longevity-genie/opengenes-mcp

longevity-genie/synergy-age-mcp

🎖️ 🐍 🏠 ☁️ - MCP server for the SynergyAge database of synergistic and antagonistic genetic interactions in longevity.

github.com/longevity-genie/synergy-age-mcp

betterhyq/mermaid-grammer-inspector-mcp

A Model Context Protocol (MCP) server for validating Mermaid diagram syntax and providing comprehensive grammar checking capabilities

github.com/betterhyq/mermaid_grammer_inspector_mcp

hlydecker/ucsc-genome-mcp

MCP server to interact with the UCSC Genome Browser API, letting you find genomes, chromosomes, and more.

github.com/hlydecker/ucsc-genome-mcp

dnaerys/onekgp-mcp

☕ ☁️ - natural language access to 1000 Genomes Project dataset

github.com/dnaerys/onekgp-mcp